Article

iSPHYNCS: Unsupervised clustering in questionnaires and metadata reveals distinct subtypes in the narcolepsy borderland

2025-03-25

Abstract excerpt

<h4>Objective</h4> The international Swiss Primary Hypersomnolence and Narcolepsy Cohort Study (iSPHYNCS) is a multicenter study aimed at identifying novel biomarkers for central disorders of hypersomnolence (CDH). We analyzed questionnaires and metadata to uncover distinct clusters of participants and explore phenotypic variability within CDH. <h4>Methods</h4> Data were collected from 227 patients with CDH and 33...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e6f09bf6-37da-5d21-ac11-fb8a2b29ef04
DOI: 10.1101/2025.03.25.25324595

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

iSPHYNCS: Unsupervised clustering in questionnaires and metadata reveals distinct subtypes in the narcolepsy borderlandDOI 10.1101/2025.03.25.25324595Read

The European Narcolepsy Network (EU-NN) database.Semantic proximity Read

Nocturnal sleep phenotypes in idiopathic hypersomnia - A data-driven cluster analysis.Semantic proximity Read

PREPRINT: Cluster analysis of ME/CFS symptoms in DecodeME reveals two subgroups and a link to onset typeSemantic proximity Read

The 103,200-arm acceleration dataset in the UK Biobank revealed a landscape of human sleep phenotypes.Semantic proximity Read

Clinical and genetic associations for night eating syndrome in a patient biobankSemantic proximity Read

Clusters of sleep apnoea phenotypes: A large pan-European study from the European Sleep Apnoea Database (ESADA).Semantic proximity Read

[Narcolepsy].Semantic proximity Read

Stratifying Eating Disorders with Clustering: From Diagnosis to Phenotypic DiversitySemantic proximity Read

Cluster-derived obstructive sleep apnea phenotypes and outcomes at 5-year follow-up.Semantic proximity Read

Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study.Semantic proximity Read

Exploring the Literature on Narcolepsy: Insights into the Sleep Disorder That Strikes during the DaySemantic proximity Read

The Role of Cluster Analysis in Precision Psychiatry: A Systematic Review of Subgroup Identification in Psychiatric DisordersSemantic proximity Read