Article
Cluster-derived obstructive sleep apnea phenotypes and outcomes at 5-year follow-up.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine - 1 Feb 2022
Silveira María Guadalupe, Sampol Gabriel, Mota-Foix Miriam, Ferrer Jaume, Lloberes Patricia
Abstract excerpt
STUDY OBJECTIVES: Obstructive sleep apnea (OSA) is a heterogeneous, complex disease. We aimed to identify OSA phenotypes through cluster analysis and to perform a long-term follow-up to validate the phenotypes. METHODS: We applied a partitioning around medioids technique in a cohort of 1,217 participants recently diagnosed with OSA. We performed a 5-year follow-up analyzing the incidence of comorbidities, chronic...
Topics
- Aged
- Continuous Positive Airway Pressure
- Female
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Phenotype
- Proportional Hazards Models
- Sleep Apnea, Obstructive