Article

Estimating the Effects of Treatment Regimes over the Course of Chronic Disease: A Multi-state Causal Framework with Baseline Confounding

2025-07-25

Abstract excerpt

<h4>ABSTRACT</h4> The development of chronic disease is a long-term process that involves multiple endpoints, and few methods can assess the health benefits of a treatment regime over the disease course. Existing multi-state Cox models estimate survival risks by state over time, which are difficult to use when comparing the effectiveness of treatment regimes. A discrete-time split-state framework has been propose...

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Literature Corpus work: e693678f-c329-5af7-8665-0f786667482b
DOI: 10.1101/2025.07.25.25332203

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