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Identification of heterokaryon incompatibility genes in <i>Aspergillus fumigatus</i> highlights a narrow footprint of ancient balancing selection

2022-11-25

Abstract excerpt

In fungi, a phenomenon termed heterokaryon incompatibility restricts hyphal fusion to occur within an individual since fusion between individuals leads to cell death. Generally, the genes involved are found to be under balancing selection from negative frequency dependent fitness. Here, we assess this in Aspergillus fumigatus , a human pathogenic fungus with an extremely high crossover rate. Using auxotrophic mar...

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Literature Corpus work
e66964a1-b5b6-5faa-aae2-7ed0c8334898
DOI
10.1101/2022.11.25.517501
Open publication

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Identification of heterokaryon incompatibility genes in <i>Aspergillus fumigatus</i> highlights a narrow footprint of ancient balancing selectionDOI 10.1101/2022.11.25.517501
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