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The human fungal pathogen Aspergillus fumigatus can produce the highest known number of meiotic crossovers

14 Sept 2023

Abstract excerpt

Sexual reproduction involving meiosis is essential in most eukaryotes. This produces offspring with novel genotypes, both by segregation of parental chromosomes as well as crossovers between homologous chromosomes. A sexual cycle for the opportunistic human pathogenic fungus Aspergillus fumigatus is known, but the genetic consequences of meiosis have remained unknown. Among other Aspergilli, it is known that A....

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PMID: 37708139
DOI: 10.1371/journal.pbio.3002278

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