Article

Mapping the gene space at single-cell resolution with gene signal pattern analysis

2023-11-27

Abstract excerpt

In single-cell sequencing analysis, several computational methods have been developed to map the cellular state space, but little has been done to map or create embeddings of the gene space. Here, we formulate the gene embedding problem, design tasks with simulated single-cell data to evaluate representations, and establish ten relevant baselines. We then present a graph signal processing approach we call gene si...

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Literature Corpus work: e6552859-4882-510a-85c5-0451cc83b4cc
DOI: 10.1101/2023.11.26.568492

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