Article

Dynamic simulations of microbial communities under perturbations: opportunities for microbiome engineering

2020-02-25

Abstract excerpt

<title>Abstract</title> <p>Background : There are few large longitudinal microbiome studies, and fewer that include controlled, well-annotated perturbations between sampling-points. Thus, there are few opportunities to employ data-driven computational analyses of perturbed microbial communities over time. Results : Our novel computational system simulates the dynamics of microbial communities under perturbations...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e600a05c-a72a-5f57-b595-9d2c668566e9
DOI: 10.21203/rs.2.24431/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dynamic simulations of microbial communities under perturbations: opportunities for microbiome engineeringDOI 10.21203/rs.2.24431/v1Read

MDPbiome: microbiome engineering through prescriptive perturbationsSemantic proximity Read

MiSDEED: a synthetic multi-omics engine for microbiome power analysis and study designSemantic proximity Read

Microbiome Modeling: A Beginner’s GuideSemantic proximity Read

<i>µ</i> bialSim: constraint-based dynamic simulation of complex microbiomesSemantic proximity Read

Bayesian inference captures metabolite-bacteria interactions in a microbial communitySemantic proximity Read

MIGRENE: The toolbox for microbial and individualized GEMs, reactobiome and community network modellingSemantic proximity Read

Microbial dynamics inference at ecosystem-scaleSemantic proximity Read

MICOM: Metagenome-Scale Modeling To Infer Metabolic Interactions in the Gut MicrobiotaSemantic proximity Read

Consistency across multi-omics layers in a drug-perturbed gut microbial communitySemantic proximity Read

Deep Learning Enables Design of Multifunctional Synthetic Human Gut Microbiome DynamicsSemantic proximity Read

MICOM: metagenome-scale modeling to infer metabolic interactions in the gut microbiotaSemantic proximity Read

Function-Based Selection of Synthetic Communities Enables Mechanistic Microbiome StudiesSemantic proximity Read