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Bayesian and frequentist meta-analysis of GCB-classification heterogeneity in TP53-reporting DLBCL cohorts at small k: a methodological exemplar

2026-06-19

Abstract excerpt

<title>Abstract</title> <p> <bold>Background.</bold> Meta-analyses of biomarker prevalence in diffuse large B-cell lymphoma (DLBCL) frequently rest on a small number of cohorts (k ≤ 5) and are correspondingly fragile: between-study heterogeneity statistics destabilize, publication-bias diagnostics become inestimable, and conventional priors begin to dominate posteriors. We use the specific case of DLBCL cohorts...

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Literature Corpus work
e44b7505-ae71-57b2-9cb3-0283d136f038
DOI
10.21203/rs.3.rs-9853529/v1
Open publication

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Bayesian and frequentist meta-analysis of GCB-classification heterogeneity in TP53-reporting DLBCL cohorts at small k: a methodological exemplarDOI 10.21203/rs.3.rs-9853529/v1
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