Article
UPLC-Q/TOF-MS-Based Phytochemical Profiling of Guizhi Powder and Its Potential Protective Mechanism Against PRRSV-Induced Lung Injury via Pseudo-time Network Pharmacology, Molecular Docking and Dynamics Simulation
2025-08-24
Abstract excerpt
This study systematically investigated the potential of Guizhi Powder to treat lung injury induced by porcine reproductive and respiratory syndrome virus infection. Guizhi Powder a classic medicine formula known for heat-clearing and detoxifying properties, was selected for analysis. Guizhi Powder was profiled via UPLC-Q/TOF-MS in positive and negative ion modes, identifying 82 high-confidence compounds. Pseudo...
Topics
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- Computational Drug Discovery Methods
- COVID-19 Clinical Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lung Cancer Treatments and Mutations
- Pharmacological Effects of Natural Compounds
- Quinazolinone synthesis and applications
- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
Identifiers and source
- Literature Corpus work
- e40723a9-d728-5110-afdc-5175d0bc2e78
- DOI
- 10.22541/au.175606037.73303317/v1
