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Possible SARS-coronavirus 2 Inhibitor Revealed By Simulated Molecular Docking to Viral Main Protease and Host toll-like Receptor

2020-06-01

Abstract excerpt

Aim: SARS-coronavirus 2 main protease (Mpro) and host toll-like receptors (TLRs) were targeted to screen potential inhibitors among traditional antiviral medicinal plants. Materials & methods: LeDock software was adopted to determine the binding energy between candidate molecules and selected protein pockets. Enrichment analyses were applied to illustrate potential pharmacology networks of active molecules. Result...

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Literature Corpus work
9330b267-178d-5f26-9b33-c6c3d303c236
DOI
10.2217/fvl-2020-0099
Open publication

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