Article

Exploring the prognostic necroptosis-related genes and underlying mechanism in sepsis using bioinformatics

2023-10-29

Abstract excerpt

Sepsis is a life-threatening disease due to a dysregulated host response to infection, with an unknown regulatory mechanism for prognostic necroptosis-related genes (NRGs). Using GEO datasets GSE65682 and GSE134347, we identified six NRG biomarkers (ATRX, TSC1, CD40, BACH2, BCL2, and LEF1) with survival and diagnostic significance through Kaplan-Meier (KM) and ROC analyses. The ingenuity pathway analysis (IPA) hig...

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Literature Corpus work: e3fec5ba-b647-5c2d-b074-eb27390b7f90
DOI: 10.21203/rs.3.rs-3491771/v1

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