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Bioinformatic analysis and experimental validation of ursolic acid’s effects on <i>Staphylococcus aureus</i> -induced osteomyelitis

2025-10-13

Abstract excerpt

Osteomyelitis (OM), particularly methicillin-resistant Staphylococcus aureus (MRSA)-induced OM, remains a serious clinical challenge due to complex pathogenesis and rising antibiotic resistance. This study aimed to elucidate the therapeutic mechanism of ursolic acid (UA) against MRSA- induced OM using integrated network pharmacology, bioinformatics, and experimental validation. Through target prediction and multi...

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Literature Corpus work
e3fc02d0-67b6-5822-ad40-2c5d6c19de4c
DOI
10.1101/2025.10.10.681659
Open publication

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Bioinformatic analysis and experimental validation of ursolic acid’s effects on <i>Staphylococcus aureus</i> -induced osteomyelitisDOI 10.1101/2025.10.10.681659
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