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Immunotherapy of cytomegalovirus infection by low-dose adoptive transfer of antiviral CD8 T cells relies on substantial post-transfer expansion of central memory cells but not effector-memory cells

2023-09-01

Abstract excerpt

Cytomegaloviruses (CMVs) are host species-specific in their replication. It is a hallmark of all CMVs that productive primary infection is controlled by concerted innate and adaptive immune responses in the immunocompetent host. As a result, the infection usually passes without overt clinical symptoms and develops into latent infection, referred to as ‘latency’. During latency, the virus is maintained in a non-rep...

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Literature Corpus work: e3740506-4198-5e75-8a45-65742c995f45
DOI: 10.1101/2023.08.31.555660

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