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IGH rod-like tracer: An AlphaFold2 structural similarity extraction-based predictive biomarker for minimal residual disease monitoring in children with precursor B-cell acute lymphoblastic leukemia

2022-09-23

Abstract excerpt

<title>Abstract</title> <p>Sequence variation resulting from the evolution of IGH clones and immunophenotypic drift makes it difficult to track abnormal B cells in children with precursor B-cell acute lymphoblastic leukemia (pre-B-ALL) by flow cytometry, quantitative polymerase chain reaction (qPCR), or next-generation sequencing (NGS). This study aimed to identify immunoglobulin heavy-chain genes (IGH) rod-like...

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Literature Corpus work
e31ca898-6344-5f23-adc0-c1fb5e56792c
DOI
10.21203/rs.3.rs-2071325/v1
Open publication

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IGH rod-like tracer: An AlphaFold2 structural similarity extraction-based predictive biomarker for minimal residual disease monitoring in children with precursor B-cell acute lymphoblastic leukemiaDOI 10.21203/rs.3.rs-2071325/v1
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