Article

Clinical application of next-generation sequencing-based monitoring of minimal residual disease in childhood acute lymphoblastic leukemia

2022-04-20

Abstract excerpt

<h4>Background: </h4> Next-generation sequencing (NGS) is an emerging technology that can comprehensively assess the diversity of the immune system. We explored the feasibility of NGS in detecting minimal residual disease (MRD) in childhood acute lymphoblastic leukemia (ALL) based on immunoglobulin and T cell receptor. <h4>Methods:</h4> Bone marrow samples were collected pre- and post-treatment with pediatric ALL...

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Literature Corpus work: 0d8ea318-033d-5145-ab56-3ae34360d765
DOI: 10.22541/au.165044019.97665119/v1

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