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Early Vascular Aging and Subclinical Myocardial Deformation in Children with β-Thalassemia Major: The Role of Asymmetric Dimethylarginine

2026-02-24

Abstract excerpt

<h4>Background: </h4> Children with β-thalassemia major (β-TM) survive longer due to advances in transfusion and chelation therapy; however, cardiovascular complications have emerged as a leading cause of long-term morbidity. Chronic hemolysis, oxidative stress, and iron overload may promote early endothelial dysfunction and premature vascular aging, yet their impact on myocardial deformation in pediatric patients...

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Literature Corpus work
e2a66e5c-1d82-5eba-bf0d-664c9a7a2e3c
DOI
10.20944/preprints202602.1453.v1
Open publication

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