Article

Broadly neutralizing human monoclonal antibodies against BK polyomavirus genotypes

2024-12-21

Abstract excerpt

<h4>ABSTRACT</h4> BK polyomavirus (BKV) causes polyomavirus-associated nephropathy (BKV-nephropathy) and polyomavirus-associated hemorrhagic cystitis (BKV-HC) following kidney transplantation and allogeneic hematopoietic stem cell transplantation (HSCT). BKV strains consist of four distinct genotypes (BKV-I, - II, -III, and -IV) with more than 80% of individuals seropositive for the BKV-I genotype, and lower prev...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e2a03f46-c751-5941-a177-1be9ac541672
DOI: 10.1101/2024.12.18.629307

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Broadly neutralizing human monoclonal antibodies against BK polyomavirus genotypesDOI 10.1101/2024.12.18.629307Read

Broadly neutralizing human monoclonal antibodies against BK polyomavirus genotypes.Semantic proximity Read

Commercially available immunoglobulins contain virus neutralizing antibodies against all major genotypes of polyomavirus BK.Semantic proximity Read

Using LIBRA-seq to map the BK-polyomavirus specific B-cell response in kidney transplant recipientsSemantic proximity Read

The humoral response to BK polyomavirus in kidney transplant recipients is dominated by IgM antibodies that use a distinct repertoire compared to IgG against the same antigenSemantic proximity Read

Natural and patient-derived mutations in BK polyomavirus VP1 reveal structural determinants of BC-loop dependent antibody escapeSemantic proximity Read

BK polyomavirus genotypes represent distinct serotypes with distinct entry tropism.Semantic proximity Read

Structural characterization of human neutralizing antibodies against JC and BK polyomaviruses.Semantic proximity Read

Structural implications of BK polyomavirus sequence variations in the major viral capsid protein Vp1 and large T-antigen: a computational studySemantic proximity Read

BK polyomavirus diversity-Why viral variation matters.Semantic proximity Read

BK Polyomavirus Diversity After Hematopoietic Stem Cell TransplantationSemantic proximity Read

BK polyomavirus genotypes in renal transplant recipients in the United States: A meta-analysis.Semantic proximity Read

Intravenous Immunoglobulin Administration Significantly Increases BKPyV Genotype-Specific Neutralizing Antibody Titers in Kidney Transplant RecipientsSemantic proximity Read