Article
Comparative genomic, phenotypic, and clinical characterization of ST11-KL25 and ST11-KL64 hypervirulent carbapenem-resistant Klebsiella pneumoniae in a tertiary hospital, 2020-2023.
Antimicrobial agents and chemotherapy - 1 Apr 2026
Li Ping, Xiao Yanghua, Luo Ruihang, Zhang Jingwen, Nie Feng, Zou TianYu, Liu Yang, Zhang Wei, Xiang Tianxin
Abstract excerpt
Hypervirulent carbapenem-resistant Klebsiella pneumoniae (hv-CRKP) poses a significant challenge in healthcare settings due to its combination of high virulence and multidrug resistance. In China, ST11 is the predominant lineage, with KL64 and the recently identified KL25 as key capsular subtypes. The clinical and genomic characteristics of ST11-KL25 remain insufficiently characterized. A total of 239 hv-CRKP...
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