Article

Invasion by <i>Fusobacterium nucleatum</i> Causes Upregulation of <i>dll4</i> and <i>klf4</i> Expression in Caco2 Cells

2020-10-26

Abstract excerpt

Fusobacterium nucleatum is an emerging microbe of importance in the pathogenesis of colorectal cancer. Strains of this enigmatic bacterial species vary in their capacity to invade human epithelial cells, a virulence determinant which has important implications in disease. Here, we infected human colorectal epithelial (Caco-2) cells in vitro with a known, highly invasive strain of F. nucleatum isolated from a Cro...

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Literature Corpus work: e20585a7-b341-56ca-9e8d-6a9cea1a3af0
DOI: 10.1101/2020.10.26.354910

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