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Article

Modelling the role of dual specificity phosphatases in Herceptin resistant breast cancer cell lines

2019-01-23

Abstract excerpt

<h4>Background</h4> Breast cancer remains the most lethal type of cancer for women. A significant proportion of breast cancer cases are characterised by overexpression of the human epidermal growth factor receptor 2 protein (HER2). These cancers are commonly treated by Herceptin (Trastuzumab), but resistance to drug treatment frequently develops in tumour cells. Dual-specificity phosphatases (DUSPs) are thought t...

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Literature Corpus work
e1352913-a9df-5bb5-a202-0f1c3fe01fc8
DOI
10.1101/528315
Open publication

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Modelling the role of dual specificity phosphatases in Herceptin resistant breast cancer cell linesDOI 10.1101/528315
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