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Identification of ferroptosis-associated genes exhibiting altered expression in pulmonary arterial hypertension

1 Jan 2021

Abstract excerpt

Pulmonary arterial hypertension (PAH) is a life-threatening illness and ferroptosis is an iron-dependent form of regulated cell death, driven by the accumulation of lipid peroxides to levels that are sufficient to trigger cell death. However, only few studies have examined PAH-associated ferroptosis. In the present study, lung samples mRNA expression profiles (derived from 15 patients with PAH and 11 normal...

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PMID: 34814266
DOI: 10.3934/mbe.2021377

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