Article

Sox10 is required for systemic initiation of bone mineralization

2024-07-24

Abstract excerpt

Heterozygous variants in the gene encoding the SOX10 transcription factor cause congenital syndromes affecting pigmentation, digestion, hearing, and neural function. Most of these symptoms are attributable to failed differentiation and loss of neural crest cells. Extensive research on mouse and zebrafish models has confirmed that Sox10 is essential for most non-skeletal crest derivatives, but seemingly dispensable...

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Literature Corpus work: e0b6caad-cce9-5917-823a-9056527fa68b
DOI: 10.1101/2024.07.24.604990

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