Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple Developmental Defects in sox11a Mutant Zebrafish with Features of Coffin-Siris Syndrome

1 Jan 2020

Abstract excerpt

A previous study suggested that human Coffin-Siris syndrome is related to the mutation of SOX11. Since the homozygous SOX11 mutant mice died soon after birth, no suitable model was available for the study of the pathogenic mechanism of Coffin-Siris syndrome. To solve this problem, we generated two viable homozygous zebrafish mutants, sox11a m/m and sox11b m/m . We found that the sox11a m/m mutant possessed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Chromatin Remodeling and Cancer
Share to Protein Degradation and Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33061816
DOI: 10.7150/ijbs.47510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple Developmental Defects in sox11a Mutant Zebrafish with Features of Coffin-Siris SyndromePMID 33061816Read ↗

Identification of a novel phenotype of external ear deformity related to Coffin-Siris syndrome-9 and literature review.Semantic proximity Read ↗

De novo SOX11 mutations cause Coffin-Siris syndrome.Semantic proximity Read ↗

A Coffin-Siris syndrome-associated mutation modeled in Caenorhabditis elegans affects multiple developmental processes.Semantic proximity Read ↗

Regulatory roles for SOX11 in development, stem cells and cancerSemantic proximity Read ↗

A rare Coffin-Siris syndrome induced by SOX11: a de novo nonsense variant of short stature.Semantic proximity Read ↗

Temtamy preaxial brachydactyly syndrome is caused by loss-of-function mutations in chondroitin synthase 1, a potential target of BMP signaling.Semantic proximity Read ↗

Maternal transmission of a mild Coffin-Siris syndrome phenotype caused by a SOX11 missense variant.Semantic proximity Read ↗

Coffin-Siris syndrome and cardiac anomaly with a novel SOX11 mutation.Semantic proximity Read ↗

Deletions and de novo mutations of <i>SOX11</i> are associated with a neurodevelopmental disorder with features of Coffin–Siris syndromeSemantic proximity Read ↗

SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling.Semantic proximity Read ↗

Japanese medaka Olpax6.1 mutant as a potential model for spondylo-ocular syndrome.Semantic proximity Read ↗

Generation of a new <i>six1</i> -null line in <i>Xenopus tropicalis</i> for study of development and congenital diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.