Article

Quantification of Human DNA from Century-Old Archived FFPE Samples for Retrospective Genomic Studies

2025-10-17

Abstract excerpt

<h4>Background</h4> Formalin-fixed, paraffin-embedded (FFPE) tissue archives are an invaluable resource for genomic research, offering the potential to link genomic data to long-term clinical outcomes. Their utility has however been limited by the degradation caused by fixation and long-term storage, particularly for samples archived for many decades. <h4>Methods</h4> This study evaluates a cohort of 79 FFPE tis...

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Literature Corpus work: e04dd6f2-219a-5d50-8b6d-6e2e6d6973a3
DOI: 10.1101/2025.10.17.681771

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