Article

Molecular typing guiding treatment and prognosis of endometrial cancer

2023-03-01

Abstract excerpt

Abstract Genetic abnormalities, such asPTEN, PIK3CA,CTNNB1,ARID1A, andERBB2, which frequently occur in endometrial cancer (EC), are potential therapeutic targets. In 2013, integrated genomic analysis conducted by The Cancer Genome Atlas identified four molecular subtypes, including POLE ultra-mutated, microsatellite instability hypermutated, copy-number low, and copy-number high, which strongly correlate with prog...

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Literature Corpus work: dfcdb5bf-00c8-50b2-b7e3-c92f2a58308c
DOI: 10.1016/j.gocm.2023.01.011

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