Article

Biosynthesis and function of tetrahydrobiopterin

1991-08-01

Abstract excerpt

Tetrahydrobiopterin (BH4) belongs to the class of pteridines (fused pyrimidopyrazines) possessing a 2-amino-4-oxo substitution of the pyrimidine moiety. BH4 is the coenzyme for tyrosine, tryptophan, and phenylalanine hydroxylases,- for the glycerol ether monooxygenase; and probably for the arginine utilizing nitric oxide synthase in rodent macrophages. The function of BH4 in these reactions derives from the abilit...

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Literature Corpus work: dfbbc4e5-3135-5ed6-bde7-b09dab57cdbc
DOI: 10.1016/0955-2863(91)90110-q

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