Article

Bone Marrow-Derived AXL Tyrosine Kinase Promotes Mitogenic Crosstalk and Cardiac Allograft Vasculopathy

2021-02-05

Abstract excerpt

<h4>ABSTRACT</h4> Cardiac Allograft Vasculopathy (CAV) is a leading contributor to late transplant rejection. Although implicated, the mechanisms by which bone marrow-derived cells promote CAV remain unclear. Emerging evidence implicates the cell surface receptor tyrosine kinase AXL to be elevated in rejecting human allografts. AXL protein is found on multiple cell types, including bone marrow-derived myeloid cel...

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Literature Corpus work: df86d022-c1c7-5f01-abdb-8de2c9404f3f
DOI: 10.1101/2021.02.04.429773

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