Article

Dual RNA sequencing (dRNA-Seq) of bacteria and their host cells

2017-01-06

Abstract excerpt

Bacterial pathogens subvert host cells by manipulating cellular pathways for survival and replication; in turn, host cells respond to the invading pathogen through cascading changes in gene expression. Deciphering these complex temporal and spatial dynamics to identify novel bacterial virulence factors or host response pathways is crucial for improved diagnostics and therapeutics. Dual RNA sequencing (dRNA-Seq) ha...

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Literature Corpus work: df096cd2-874f-56eb-a6bf-99ec72defc7c
DOI: 10.1101/098715

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