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Resolving host–pathogen interactions by dual RNA-seq

16 Feb 2017

Abstract excerpt

The transcriptome is a powerful proxy for the physiological state of a cell, healthy or diseased. As a result, transcriptome analysis has become a key tool in understanding the molecular changes that accompany bacterial infections of eukaryotic cells. Until recently, such transcriptomic studies have been technically limited to analyzing mRNA expression changes in either the bacterial pathogen or the infected...

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PMID: 28207848
DOI: 10.1371/journal.ppat.1006033

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