Article

Bioinformatics and Connectivity Map Analysis Suggest Viral Infection as a Critical Causative Factor of Hashimoto’s Thyroiditis

2022-12-15

Abstract excerpt

Hashimoto’s thyroiditis (HT) is a common autoimmune disease, with its prevalence rapidly increasing. Both genetic and environmental risk factors contribute to the development of HT. Recently, viral infection has been suggested to act as a trigger of HT by eliciting the host immune response and subsequent autoreactivity. We analyzed features of HT through bioinformatics analysis so as to identify markers of H...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2a7d6b50-1116-5b0a-9ded-46270c72601f
DOI: 10.20944/preprints202212.0275.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bioinformatics and Connectivity Map Analysis Suggest Viral Infection as a Critical Causative Factor of Hashimoto’s ThyroiditisDOI 10.20944/preprints202212.0275.v1Read

Integrative Analyses of Genes Associated with Hashimoto's Thyroiditis.Semantic proximity Read

Bioinformatics-Based Study to Investigate Potential Differentially Expressed Genes and miRNAs in Hashimoto’s ThyroiditisSemantic proximity Read

Bioinformatics analysis of key genes and pathways in Hashimoto thyroiditis tissuesSemantic proximity Read

Comparative Transcriptomic Analysis of Pathogenic Mechanisms in Papillary Thyroid Carcinoma and Hashimoto's ThyroiditisSemantic proximity Read

CD27 exhibits clinical diagnostic value and reveals the immune heterogeneity as well as predicts clinical drug responses in hashimoto's thyroiditisSemantic proximity Read

Identification of BTK as an immune-related biomarker for Hashimoto’s thyroiditis by integrated bioinformatic analysisSemantic proximity Read

Bioinformatics analysis identified shared differentially expressed genes as potential biomarkers for Hashimoto's thyroiditis-related papillary thyroid cancerSemantic proximity Read

<i>In silico</i> transcriptomic analysis reveals shared molecular signatures and immune-associated pathways between Hashimoto’s thyroiditis and type 2 diabetes with exploratory drug repurposingSemantic proximity Read

Decoding Hashimoto’s Thyroiditis: Key Genes and Pathways in Inflammation and PyroptosisSemantic proximity Read

Identifying and analyzing the key genes shared by papillary thyroid carcinoma and Hashimoto’s thyroiditis using bioinformatics methodsSemantic proximity Read

Integrative analysis of gut microbiome and host transcriptome reveal novel molecular signatures in Hashimoto's thyroiditisSemantic proximity Read

Genetic relationship between Hashimoto`s thyroiditis and papillary thyroid carcinoma with coexisting Hashimoto`s thyroiditis.Semantic proximity Read