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Article

Comparison of volumetric dynamic optical coherence tomography with biological methods for evaluation of radiation effects in prostate tumor spheroids

2025-11-10

Abstract excerpt

<h4>Significance</h4> 3D tumor spheroids are more physiologically representative of in vivo patient tumors compared to 2D monolayer culture. However, their 3D nature challenges the use of conventional biological techniques like proliferation assays, fluorescence microscopy, and the clonogenic assay, which is the gold standard method for assessing cell survival following radiation. However, clonogenic assay requi...

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Literature Corpus work
debc8cc0-230c-50ff-9d29-f927d97a3ff1
DOI
10.1101/2025.11.08.687368
Open publication

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Comparison of volumetric dynamic optical coherence tomography with biological methods for evaluation of radiation effects in prostate tumor spheroidsDOI 10.1101/2025.11.08.687368
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