Article
Radioresistance of prostate cancer cells with low proteasome activity.
The Prostate - 1 Jun 2012
Della Donna Lorenza, Lagadec Chann, Pajonk Frank
Abstract excerpt
BACKGROUND: Prostate cancer is frequently treated with radiotherapy. While treatment results are in general excellent, some patients relapse and current systemic therapies are not curative, thus, underlining the need for novel targeted therapies. Proteasome inhibitors have been suggested as promising new agents against solid tumors including prostate cancer but initial results from clinical trials are...
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