Back to search

Article

Mutation patterns of human SARS-COV-2 and bat RaTG13 coronaviruses genomes are strongly biased towards C>U indicating rapid evolution in their hosts

2020-04-07

Abstract excerpt

<title>Abstract</title> <p>Background: The world pandemy caused by SARS-CoV-2 spreading has raised considerable interest about its evolutionary origin and genome structure. Here we analysed mutation patterns in 13 human SARS-COV-2 isolates and a closely related RaTG13 isolated from <italic>Rhinolophus affinis</italic> bat. We also evaluated the CpG dinucleotide contents in SARS-COV-2 and other human and animal co...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
deba63d5-a30b-56d3-a4d9-3c93a04620c8
DOI
10.21203/rs.3.rs-21377/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Mutation patterns of human SARS-COV-2 and bat RaTG13 coronaviruses genomes are strongly biased towards C&gt;U indicating rapid evolution in their hostsDOI 10.21203/rs.3.rs-21377/v1
Mutation Patterns of Human SARS-CoV-2 and Bat RaTG13 Coronavirus Genomes Are Strongly Biased Towards C>U Transitions, Indicating Rapid Evolution in Their Hosts.Semantic proximity
Comparative genomic analysis revealed specific mutation pattern between human coronavirus SARS-CoV-2 and Bat-SARSr-CoV RaTG13Semantic proximity
Comparative Genomic Analyses Reveal a Specific Mutation Pattern Between Human Coronavirus SARS-CoV-2 and Bat-CoV RaTG13Semantic proximity
Rampant C->U hypermutation in the genomes of SARS-CoV-2 and other coronaviruses – causes and consequences for their short and long evolutionary trajectoriesSemantic proximity
Excessive G–U transversions in novel allele variants in SARS-CoV-2 genomesSemantic proximity
Genetic spectrum and distinct evolution patterns of SARS-CoV-2Semantic proximity
Genetic Spectrum and Distinct Evolution Patterns of SARS-CoV-2Semantic proximity
Mutation signatures inform the natural host of SARS-CoV-2Semantic proximity
Rampant C→U Hypermutation in the Genomes of SARS-CoV-2 and Other Coronaviruses: Causes and Consequences for Their Short- and Long-Term Evolutionary Trajectories.Semantic proximity
A selective sweep in the <i>Spike</i> gene has driven SARS-CoV-2 human adaptationSemantic proximity
Evolutionary Shift from Purifying Selection towards Divergent Selection of SARS-CoV2 Favors its Invasion into Multiple Human OrgansSemantic proximity
Where Did SARS-CoV-2 Come From?Semantic proximity
Select a neighboring publication to make it the new centre.