Article

Menadione reduces the expression of virulence- and colonisation-associated genes in <i>Helicobacter pylori</i>

2024-11-07

Abstract excerpt

Novel treatment options are needed for the gastric pathogen Helicobacter pylori due to its increasing antibiotic resistance. The vitamin K analogue menadione has been extensively studied due to interest in its antibacterial and anti-cancer properties. Here, we investigated the effects of menadione on H. pylori growth, viability, antibiotic resistance, motility and gene expression using clinical isolates. The min...

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Literature Corpus work: de9f81cc-1bc9-53e7-8523-48022e95d6a2
DOI: 10.1101/2024.11.07.622476

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