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Helicobacter pylori outer membrane protein HopQ identified as a novel T4SS-associated virulence factor

20 Jun 2013

Abstract excerpt

Helicobacter pylori is a bacterial pathogen that colonizes the gastric niche of ∼ 50% of the human population worldwide and is known to cause peptic ulceration and gastric cancer. Pathology of infection strongly depends on a cag pathogenicity island (cagPAI)-encoded type IV secretion system (T4SS). Here, we aimed to identify as yet unknown bacterial factors involved in cagPAI effector function and performed a...

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PMID: 23782461
DOI: 10.1111/cmi.12158

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