Article

Developing Virtual Personas from User-Level Social Media Data: Stability and Human Alignment of LLM-Generated Symptom Profiles

2026-07-24

Abstract excerpt

Large language models (LLMs) may support realistic virtual patients, yet most existing systems rely on top-down construction approaches, such as manually curated vignettes. We investigated a bottom-up alternative in which social media histories were transformed into virtual personas examining stability and alignment with human judgment. Histories from Italian Reddit users reporting depressive or anxiety-related di...

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Literature Corpus work: de908abf-28f2-54e8-ab9a-6f9698111f98
DOI: 10.20944/preprints202607.1828.v1

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