Article

Allosteric perspective on the mutability and druggability of the SARS-CoV-2 Spike protein

2021-08-02

Abstract excerpt

<h4>Summary</h4> Recent developments in the SARS-CoV-2 pandemic point to its inevitable transformation into an endemic disease, urging both diagnostics of emerging variants of concern (VOCs) and design of the variant-specific drugs in addition to vaccine adjustments. Exploring the structure and dynamics of the SARS-CoV-2 Spike protein, we argue that the high mutability characteristic of RNA viruses coupled with t...

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Literature Corpus work: de5318f7-b8e0-5f98-838d-0012bf722bc9
DOI: 10.1101/2021.08.01.454696

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