Article

Extracellular vesicle microRNA cargo engineering reveals critical mechanisms underlying therapeutic efficacy

2022-01-31

Abstract excerpt

<h4>Background</h4> Extracellular vesicles (EVs) are key mediators of intercellular communication and function to transfer biological cargo, including microRNA (miR), from donor to recipient cells. EVs isolated from cardiosphere-derived cells (CDCs) have demonstrated therapeutic efficacy in pre-clinical models of ischemic heart disease, highlighting them as promising vectors for the treatment of CVD. Importantly,...

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Literature Corpus work: de380b92-ac7f-52c1-9e2a-5d0324876977
DOI: 10.1101/2022.01.31.478505

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