Article

Upregulated complement receptors correlate with Fc gamma receptor 3A-positive natural killer and natural killer-T cells in neuromyelitis optica spectrum disorder

2022-10-14

Abstract excerpt

<h4>Background: </h4> and objectives. Inhibition of terminal complement in neuromyelitis optica spectrum disorder (NMOSD) using eculizumab helps prevent relapses, but the exact mechanism of action of the drug remains unclear. Similarly, genetic variants in the Fc Gamma receptor 3A (FcGR3A), also known as CD16, are correlated with outcomes in NMOSD, but the immune cells expressing those CD16 are unknown. We compare...

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Literature Corpus work: de127f01-1558-5349-9ebb-efe366463bb2
DOI: 10.21203/rs.3.rs-2143780/v1

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