Article
Genome-wide association study of cerebellar volume provides insights into heritable mechanisms underlying brain development and mental health.
Communications biology - 16 Jul 2022
Tissink Elleke, de Lange Siemon C, Savage Jeanne E, Wightman Douglas P, de Leeuw Christiaan A, Kelly Kristen M, Nagel Mats, van den Heuvel Martijn P, Posthuma Danielle
Abstract excerpt
Cerebellar volume is highly heritable and associated with neurodevelopmental and neurodegenerative disorders. Understanding the genetic architecture of cerebellar volume may improve our insight into these disorders. This study aims to investigate the convergence of cerebellar volume genetic associations in close detail. A genome-wide associations study for cerebellar volume was performed in a discovery sample of...
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