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Efficient differentiation of human retinal pigment epithelium cells from chemically induced pluripotent stem cells

2024-03-27

Abstract excerpt

Human induced pluripotent stem cells (hiPSCs) hold considerable promise for autologous cellular therapies, particularly in ocular disease treatment, because of the low numbers of cells required for transplantation and the non-invasive nature of graft monitoring. However, the use of hiPSCs in ocular disease treatment faces challenges because the production of clinical-grade autologous hiPSCs via genetic techniques...

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Literature Corpus work
dcfe7280-4f04-5f24-bc93-fd3d9753752b
DOI
10.1101/2024.03.22.586212
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