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Generation and characterization of human iPSC lines (FAHZJUi001-A and FAHZJUi002-A) from two familial recurrent hydatidiform mole patients carrying homozygous mutation in the NLRP7 gene

2025-07-30

Abstract excerpt

<title>Abstract</title> <p> Hydatidiform mole (HM) is a pathological pregnancy characterized by excessive trophoblast proliferation and the absence of embryonic tissue development, predominantly sporadic in onset. Recurrent hydatidiform mole (RHM) affects approximately 1%-4% of HM patients, among which familial RHM (FRHM) is extremely rare and classified as a monogenic autosomal recessive disorder. <italic>NLRP...

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Literature Corpus work
dcb8bc92-34f2-5647-bd0f-7f7b2dafd3e4
DOI
10.21203/rs.3.rs-7174273/v1
Open publication

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Generation and characterization of human iPSC lines (FAHZJUi001-A and FAHZJUi002-A) from two familial recurrent hydatidiform mole patients carrying homozygous mutation in the NLRP7 geneDOI 10.21203/rs.3.rs-7174273/v1
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