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Article

Recurrent hydatidiform mole: detection of two novel mutations in the NLRP7 gene in two Egyptian families.

European journal of obstetrics, gynecology, and reproductive biology - 1 Oct 2012

Abdalla Ebtesam M, Hayward Bruce E, Shamseddin Ahmed, Nawar Mona M

Abstract excerpt

OBJECTIVES: Hydatidiform mole is an aberrant pregnancy with hyperproliferative vesicular trophoblast and defective fetal development. In 2006, mutations in NLRP7 were found to be responsible for recurrent hydatidiform moles (RHM), but genetic heterogeneity has been demonstrated and mutations of C...

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Source

Identifiers

PMID: 22770628
DOI: 10.1016/j.ejogrb.2012.06.017

Genes

NLRP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22770628-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Recurrent hydatidiform mole: detection of two novel mutations in the NLRP7 gene in two Egyptian families.PMID 22770628Read ↗

The spectrum of NLRP7 mutations in French patients with recurrent hydatidiform mole.Semantic proximity Read ↗

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Screening for NLRP7 mutations in familial and sporadic recurrent hydatidiform moles: report of 2 Tunisian families.Semantic proximity Read ↗

Novel NLRP7 mutations in familial recurrent hydatidiform mole: are NLRP7 mutations a risk for recurrent reproductive wastage?Semantic proximity Read ↗

The p.L750V mutation in the NLRP7 gene is frequent in Mexican patients with recurrent molar pregnancies and is not associated with recurrent pregnancy loss.Semantic proximity Read ↗

NLRP7 mutation analysis in sporadic hydatidiform moles in Tunisian patients: NLRP7 and sporadic mole.Semantic proximity Read ↗

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A recurrent intragenic genomic duplication, other novel mutations in NLRP7 and imprinting defects in recurrent biparental hydatidiform moles.Semantic proximity Read ↗

The genetics of recurrent hydatidiform moles in Mexico: further evidence of a strong founder effect for one mutation in NLRP7 and its widespread.Semantic proximity Read ↗

Live births in women with recurrent hydatidiform mole and two NLRP7 mutations.Semantic proximity Read ↗

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