Article

Genetic crosses reveal genomic loci responsible for virulence in <i>Cryptosporidium parvum</i> infection

2025-05-21

Abstract excerpt

The relationship between parasite genotype and pathogenesis is largely unknown for Cryptosporidium , a leading cause of diarrheal disease in children. An array of parasites with similar genomes produces varied disease outcomes in different hosts. Here, we isolate and characterize Cryptosporidium parvum strains that show marked differences in virulence and persistence in mice. Taking advantage of the sexual lifec...

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Literature Corpus work: dc2c0fc4-23ed-5bd6-b7fe-b41b01c14b7e
DOI: 10.1101/2025.05.20.655157

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