Article
Comparative genomics of Cryptosporidium parvum reveals the emergence of an outbreak-associated population in Europe and its spread to the United States.
Genome research - 23 Jul 2024
Bellinzona Greta, Nardi Tiago, Castelli Michele, Batisti Biffignandi Gherard, Adjou Karim, Betson Martha, Blanchard Yannick, Bujila Ioana, Chalmers Rachel, Davidson Rebecca, D'Avino Nicoletta, Enbom Tuulia, Gomes Jacinto, Karadjian Gregory, Klotz Christian, Östlund Emma, Plutzer Judith, Rimhanen-Finne Ruska, Robinson Guy, Sannella Anna Rosa, Sroka Jacek, Stensvold Christen Rune, Troell Karin, Vatta Paolo, Zalewska Barbora, Bandi Claudio, Sassera Davide, Cacciò Simone M
Abstract excerpt
The zoonotic parasite Cryptosporidium parvum is a global cause of gastrointestinal disease in humans and ruminants. Sequence analysis of the highly polymorphic gp60 gene enabled the classification of C. parvum isolates into multiple groups (e.g., IIa, IIc, Id) and a large number of subtypes. In Europe, subtype IIaA15G2R1 is largely predominant and has been associated with many water- and food-borne outbreaks. In...
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