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Disruption of genes associated with Charcot-Marie-Tooth type 2 lead to common behavioural, cellular and molecular defects in <i>Caenorhabditis elegans</i>

2019-04-11

Abstract excerpt

Charcot-Marie-Tooth (CMT) disease is an inherited peripheral motor and sensory neuropathy. The disease is divided into demyelinating (CMT1) and axonal (CMT2) neuropathies, and although we have gained molecular information into the details of CMT1 pathology, much less is known about CMT2. Due to its clinical and genetic heterogeneity, coupled with a lack of animal models, common underlying mechanisms remain elusive...

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Literature Corpus work
dc28b64f-13c2-5e08-ba12-46417b872101
DOI
10.1101/605584
Open publication

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Disruption of genes associated with Charcot-Marie-Tooth type 2 lead to common behavioural, cellular and molecular defects in <i>Caenorhabditis elegans</i>DOI 10.1101/605584
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