Article
Boosting of SARS-CoV-2 immunity in nonhuman primates using an oral rhabdoviral vaccine
2021-10-18
Abstract excerpt
An orally active vaccine capable of boosting SARS-CoV-2 immune responses in previously infected or vaccinated individuals would help efforts to achieve and sustain herd immunity. Unlike mRNA-loaded lipid nanoparticles and recombinant replication-defective adenoviruses, replicating vesicular stomatitis viruses with SARS-CoV-2 spike glycoproteins (VSV-SARS2) were poorly immunogenic after intramuscular administration...
Topics
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- Animal Virus Infections Studies
- Immunotherapy and Immune Responses
- RNA Interference and Gene Delivery
- SARS-CoV-2 and COVID-19 Research
- Transgenic Plants and Applications
- vaccines and immunoinformatics approaches
- Viral gastroenteritis research and epidemiology
- Viral Infectious Diseases and Gene Expression in Insects
Identifiers and source
- Literature Corpus work
- dbb863fc-cf1a-5f3a-85e1-f5bd64e02a15
- DOI
- 10.1101/2021.10.16.464660
