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The unique lipopolysaccharide composition of <i>Salmonella</i> Typhimurium ST313 dampens pyroptosis and inflammasome activation and suppresses host cell death

2025-09-29

Abstract excerpt

<h4>ABSTRACT</h4> In humans, non-typhoidal Salmonella (NTS) serovars, such as Salmonella enterica Typhimurium cause self-limiting gastroenteritis. However, invasive non-typhoidal Salmonella (iNTS) isolates ST313 have emerged in sub-Saharan Africa that cause a severe bacteremia in immunocompromised individuals including HIV-positive adults. Despite a decade of studies comparing ST313 to the classical diarrheal...

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Literature Corpus work
db971bf5-c228-5a6a-8293-dc3f8c210c04
DOI
10.1101/2025.09.29.679141
Open publication

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