Article

Bidirectional Modulation Of Synaptic Transmission By Insulin-Like Growth Factor I

2023-12-29

Abstract excerpt

<h4>ABSTRACT</h4> Insulin-like growth factor-I (IGF-I) plays a key role in the modulation of synaptic plasticity, and is an essential factor in learning and memory processes. Indeed, we have demonstrated that IGF-IR activation induces long-term potentiation (LTP) of synaptic transmission (LTP IGF-I ) both in the barrel cortex, improving object recognition (Noriega-Prieto et al., 2021), and in the prefrontal cort...

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Literature Corpus work: db7da75c-0fcd-5bf2-84d0-1d2699858f9c
DOI: 10.1101/2023.12.29.573627

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