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A Viral Fragmentation Signature for SARS-CoV-2 in Clinical Samples Correlating with Contagiousness

2021-01-15

Abstract excerpt

The viral load of SARS-CoV-2 in clinical samples as measured by the primary diagnostic tool of RT-PCR is an imperfect readout for infection potential as most targeted assays designed for sensitivity, indiscriminately detect short and long RNA fragments, although infectivity is embodied only in the whole virus and its intact genome. Here, we used next-generation sequencing (NGS) to characterize 155 clinical samples...

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Literature Corpus work
db62ff5a-a15b-54da-8be5-85d4e607a978
DOI
10.1101/2021.01.11.21249265
Open publication

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A Viral Fragmentation Signature for SARS-CoV-2 in Clinical Samples Correlating with ContagiousnessDOI 10.1101/2021.01.11.21249265
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